{
 "exported_at": "2026-10-30T03:13:49.533100+00:00",
 "exported_by": {
  "app": "quantetta-a web",
  "code": {
   "git_commit": "",
   "dirty": false
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 "recording_short": "M13Rec001",
 "header": {
  "short": "M13Rec001",
  "label": "Mouse heart, spiral wave and optogenetic termination",
  "facts": "64 \u00d7 55 px, 9,267 frames, 1 kHz, 133 \u00b5m/px, deposit checks: negative values, nan mask all frames, temporal smoothing, spatial smoothing",
  "run_short": "c0c30a22",
  "run_when": "2026-10-27 23:30 UTC",
  "params_version": 3,
  "commit": "905d5be",
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  "workers": null,
  "sig_short": "b456870e",
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  "protocol_name": "Mouse whole heart optical mapping (Luther lab)"
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 "parameters": "% Mouse whole heart optical mapping (Luther lab), v3, read-only\n% set by developer (not a domain scientist); provisional, REVIEW_NEEDED 16\nbaseline_frames  = 901;     % >= 2 x slowest cycle (415, MAP): ok\npad_frames       = 500;     % each side, outside the window\nspatial_sigma    = 1.0;     % px, Gaussian, phase only\nspatial_truncate = 4.0;     % kernel radius, sigma\nlowpass          = [];      % none\npolarity         = -1;      % measured, skew of dV/dt\nrotor_threshold  = 0.9;     % turns, |winding| per plaquette\nrotor_erode_px   = 3;       % px from tissue edge ignored\nlink_px          = 4.0;     % tracking, max step per frame\nmax_gap          = 5;       % frames a track may vanish\nmin_cycles       = 1.0;     % own rotations, min_frames = 52\npair_dist_px     = 3.0;     % opposite-charge pairing\npaired_frac      = 0.5;     % max paired fraction of a track\nrender_step      = 4;       % movie only",
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    "illuminated_arrhythmia.persistent_rotor_count_max",
    "illuminated_arrhythmia.dominant_freq_hz",
    "illuminated_after_termination.singularity_frames_frac",
    "persistent_rotor_tracks"
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   "physiology_ok": null,
   "ranged_checks": [
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  },
  "ranges": [
   {
    "id": "mouse_spiral_rotation_hz",
    "low": 18.75,
    "high": 20.0,
    "unit": "Hz",
    "scope": "one optical mapping recording in the same study (spiral wave before and during illumination); not a population range",
    "metric": "dominant_freq_hz",
    "source": {
     "ref": "10.1371/journal.pcbi.1011660",
     "quotes": [
      "rotational frequency of \u2248 20 Hz before illumination",
      "the frequency of the arrhythmia decreases to \u2248 18\\.75 Hz"
     ],
     "passages": [
      " is shown in Fig 3B. It shows that the arrhythmia consists of a single spiral wave with a stationary core dynamic and a rotational frequency of \u2248 20 Hz before illumination. During a single global optical pulse with a PL of 5000 ms and an LI of 3.21 \u03bcW/mm2, the frequency of the arrhythmia de",
      "ncy of \u2248 20 Hz before illumination. During a single global optical pulse with a PL of 5000 ms and an LI of 3.21 \u03bcW/mm2, the frequency of the arrhythmia decreases to \u2248 18.75 Hz. It is important to note that the frequency reverses its original value of \u2248 20 Hz when the light is turned off. Fig 3C"
     ]
    },
    "status": "provisional",
    "tissue": "whole_heart",
    "species": "mouse",
    "applies_to": {
     "segment_expected_persistent_rotors": "present"
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    "checked_high": 25.0,
    "tolerance_frac": 0.25
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  ],
  "run_id": "c0c30a22-bf69-424a-8a7c-76e8fbac530d",
  "status": "provisional",
  "verdict": {
   "send_back": false,
   "critic_notes": "Verdict: report only the stable, provisional signature components; physiology_ok is null because the only cited-range check, illuminated_arrhythmia.dominant_freq_hz, is unstable across baseline windows (15.356\u201319.85 Hz) and therefore not reportable as a single value, even though the same-study context gives approximately 18.75\u201320.0 Hz and a checked range of 14.0625\u201325.0 Hz (DOI 10.1371/journal.pcbi.1011660). Reportable with caveats: stable absence of persistent rotors in light_off and illuminated_after_termination (0 across filter and tracker variants), stable light_off and illuminated_after_termination dominant frequencies of 2.375 Hz and 2.214 Hz without cited ranges, and stable illuminated_arrhythmia singularity-frame fraction as a range of 0.3816479400749064\u20130.48801498127340825 without a cited range; unstable and not reportable as single values are light_off.singularity_frames_frac (0.0029023746701846965\u20130.02955145118733509), illuminated_arrhythmia.persistent_rotors and persistent_rotor_tracks (4.0\u201315.0), illuminated_arrhythmia.persistent_rotor_count_max (1.0\u20132.0), illuminated_arrhythmia.dominant_freq_hz (15.356\u201319.85 Hz), and illuminated_after_termination.singularity_frames_frac (0.0005534034311012728\u20130.014941892639734366). The persistent-rotor rule itself holds under both min_frames 52 and min_frames 50, and strict/default/loose tracker rule verdicts agree even though counts differ; review the processed-data status, frame 3170 event interpretation, baseline/illumination artifact, and provisional thresholds. The ranges, the stability threshold and the criteria are provisional.",
   "review_items": [
    {
     "topic": "unstable:light_off.singularity_frames_frac",
     "detail": "Review the filter sensitivity before reporting the light_off singularity-frame fraction; use only the range 0.0029023746701846965\u20130.02955145118733509 for review, not a single value.",
     "severity": "warn",
     "reviewer_type": "domain scientist / signal-processing reviewer"
    },
    {
     "topic": "unstable:illuminated_arrhythmia.persistent_rotors",
     "detail": "Review rotor tracking/count sensitivity; the illuminated_arrhythmia persistent-rotor count spans 4.0\u201315.0 and is not reportable as a single count.",
     "severity": "warn",
     "reviewer_type": "domain scientist / tracking reviewer"
    },
    {
     "topic": "unstable:illuminated_arrhythmia.persistent_rotor_count_max",
     "detail": "Review concurrent rotor-count sensitivity; the maximum concurrent count spans 1.0\u20132.0 and should not be reported as a single value.",
     "severity": "warn",
     "reviewer_type": "domain scientist / tracking reviewer"
    },
    {
     "topic": "unstable:illuminated_arrhythmia.dominant_freq_hz",
     "detail": "Review baseline-window dependence of the illuminated_arrhythmia frequency; it spans 15.356\u201319.85 Hz and is not reportable as a single value despite cited same-study context (DOI 10.1371/journal.pcbi.1011660).",
     "severity": "warn",
     "reviewer_type": "domain scientist / rhythm reviewer"
    },
    {
     "topic": "unstable:illuminated_after_termination.singularity_frames_frac",
     "detail": "Review filter sensitivity before reporting the after-termination singularity-frame fraction; use only the range 0.0005534034311012728\u20130.014941892639734366 for review.",
     "severity": "warn",
     "reviewer_type": "domain scientist / signal-processing reviewer"
    },
    {
     "topic": "unstable:persistent_rotor_tracks",
     "detail": "Review persistent-track counting sensitivity; total persistent tracks span 4.0\u201315.0 and are not reportable as a single value.",
     "severity": "warn",
     "reviewer_type": "domain scientist / tracking reviewer"
    },
    {
     "topic": "Pre-deposit processing / raw-data label",
     "detail": "The README labels M13Rec001 as raw experimental data, but notebook and measurement flags indicate masking, spatial smoothing, temporal smoothing, and normalization; avoid analyses that require raw photon counts or independent pixel noise if treated as raw camera data.",
     "severity": "warn",
     "reviewer_type": "data curator / domain scientist"
    },
    {
     "topic": "Event interpretation at frame 3170",
     "detail": "Frame 3170 is a baseline_step only; illumination began before frame 0 and ended at frame 4977, so frame 3170 should not be treated as light onset. The stored spiral-termination label is provisional.",
     "severity": "warn",
     "reviewer_type": "domain scientist"
    },
    {
     "topic": "Baseline and illumination artifact",
     "detail": "Blue stimulation light crosstalk, re-normalization by stimulation light signal, a large slow baseline range, and a baseline step can affect absolute baseline or amplitude analyses.",
     "severity": "warn",
     "reviewer_type": "domain scientist / signal-processing reviewer"
    },
    {
     "topic": "Provisional tool thresholds",
     "detail": "Event detection, processing flags, SNR, rhythm, reference-rate thresholds, the stability threshold, and criteria are provisional and should be checked for critical analyses.",
     "severity": "info",
     "reviewer_type": "domain scientist"
    }
   ],
   "tracker_note": "Strict, default, and loose trackers give illuminated_arrhythmia persistent-rotor counts of 5, 13, and 15 respectively, with 0 in light_off and 0 in illuminated_after_termination for all three; despite count differences, the persistent-rotor rule verdict holds for every tracker, so the rule-level verdicts agree.",
   "physiology_ok": null,
   "metric_judgments": [
    {
     "note": "Unstable across the filter grid (range 0.0029023746701846965\u20130.02955145118733509 fraction of frames; spread_frac 3.108), so this fraction should not be reported as a single segment metric.",
     "metric": "light_off.singularity_frames_frac",
     "status": "unstable_not_reportable"
    },
    {
     "note": "Stable at 0 across filter and tracker variants, but there is no cited physiology range for this count; it may be reported only as an algorithmic absence finding under the provisional criteria.",
     "metric": "light_off.persistent_rotors",
     "status": "no_cited_range"
    },
    {
     "note": "Stable at 0 across filter and tracker variants, but no cited physiology range is available; report, if needed, as a provisional tracking result rather than a physiology-validated value.",
     "metric": "light_off.persistent_rotor_count_max",
     "status": "no_cited_range"
    },
    {
     "note": "Stable at 2.375 Hz across baseline windows, but no cited range is available for this segment, so it should not be used for physiology range validation.",
     "metric": "light_off.dominant_freq_hz",
     "status": "no_cited_range"
    },
    {
     "note": "Stable across the filter grid (range 0.3816479400749064\u20130.48801498127340825 fraction of frames), but no cited physiology range exists; it may support the provisional singularity-presence signature.",
     "metric": "illuminated_arrhythmia.singularity_frames_frac",
     "status": "no_cited_range"
    },
    {
     "note": "Unstable across filter and tracker variants (range 4.0\u201315.0 tracks; spread_frac 0.917), so the rotor count itself is not reportable as a single value; only the stable presence/absence rule may be used.",
     "metric": "illuminated_arrhythmia.persistent_rotors",
     "status": "unstable_not_reportable"
    },
    {
     "note": "Unstable across filter and tracker variants (range 1.0\u20132.0 count; spread_frac 0.5), so the maximum concurrent count should not be reported as a single value.",
     "metric": "illuminated_arrhythmia.persistent_rotor_count_max",
     "status": "unstable_not_reportable"
    },
    {
     "note": "Unstable across baseline windows (range 15.356\u201319.85 Hz; spread_frac 0.261), so it is not reportable as a single frequency even though the cited same-study context is approximately 18.75\u201320.0 Hz / checked 14.0625\u201325.0 Hz (DOI 10.1371/journal.pcbi.1011660).",
     "metric": "illuminated_arrhythmia.dominant_freq_hz",
     "status": "unstable_not_reportable"
    },
    {
     "note": "Unstable across the filter grid (range 0.0005534034311012728\u20130.014941892639734366 fraction of frames; spread_frac 2.6), so this fraction should not be reported as a single segment metric.",
     "metric": "illuminated_after_termination.singularity_frames_frac",
     "status": "unstable_not_reportable"
    },
    {
     "note": "Stable at 0 across filter and tracker variants, but no cited physiology range is available; it may be reported only as a provisional algorithmic absence finding.",
     "metric": "illuminated_after_termination.persistent_rotors",
     "status": "no_cited_range"
    },
    {
     "note": "Stable at 0 across filter and tracker variants, but no cited physiology range is available; report, if needed, as a provisional tracking result.",
     "metric": "illuminated_after_termination.persistent_rotor_count_max",
     "status": "no_cited_range"
    },
    {
     "note": "Stable at 2.214 Hz across baseline windows, but there is no cited range for this segment, so it should not be used for physiology range validation.",
     "metric": "illuminated_after_termination.dominant_freq_hz",
     "status": "no_cited_range"
    },
    {
     "note": "Unstable across filter and tracker variants (range 4.0\u201315.0 tracks; spread_frac 0.917), so the total persistent-track count is not reportable as a single value.",
     "metric": "persistent_rotor_tracks",
     "status": "unstable_not_reportable"
    }
   ],
   "send_back_reason": null,
   "persistence_threshold_note": "The persistent-rotor rule holds under both the measured-cycle threshold (min_frames 52) and the paper-rotation threshold (min_frames 50 from 1000 frames/s and 20.0 Hz, DOI 10.1371/journal.pcbi.1011660); the two verdicts agree."
  },
  "passages": {
   "mouse_spiral_rotation_period": {
    "ref": "10.1371/journal.pcbi.1011660",
    "note": "At 1000 frames/s, 20 Hz is a 50-frame rotation; the illuminated value of 18.75 Hz would be 53 frames.",
    "quotes": [
     "rotational frequency of \u2248 20 Hz before illumination"
    ],
    "status": "provisional",
    "passages": [
     " is shown in Fig 3B. It shows that the arrhythmia consists of a single spiral wave with a stationary core dynamic and a rotational frequency of \u2248 20 Hz before illumination. During a single global optical pulse with a PL of 5000 ms and an LI of 3.21 \u03bcW/mm2, the frequency of the arrhythmia de"
    ],
    "applies_to": {
     "species": "mouse"
    },
    "rotation_hz": 20.0
   }
  },
  "trackers": {
   "note": "disagreement is reported as a review item, not folded into the pass/fail",
   "agree": true,
   "trackers": [
    {
     "link_px": 2.0,
     "max_gap": 1,
     "tracker": "strict",
     "is_run_setting": false,
     "persistent_rotor_rule": "holds (provisional)",
     "persistent_rotors_by_segment": {
      "light_off": 0,
      "illuminated_arrhythmia": 5,
      "illuminated_after_termination": 0
     }
    },
    {
     "link_px": 4.0,
     "max_gap": 5,
     "tracker": "default",
     "is_run_setting": true,
     "persistent_rotor_rule": "holds (provisional)",
     "persistent_rotors_by_segment": {
      "light_off": 0,
      "illuminated_arrhythmia": 13,
      "illuminated_after_termination": 0
     }
    },
    {
     "link_px": 6.0,
     "max_gap": 10,
     "tracker": "loose",
     "is_run_setting": false,
     "persistent_rotor_rule": "holds (provisional)",
     "persistent_rotors_by_segment": {
      "light_off": 0,
      "illuminated_arrhythmia": 15,
      "illuminated_after_termination": 0
     }
    }
   ]
  },
  "stability": {
   "persistent_rotor_tracks": {
    "max": 15.0,
    "min": 4.0,
    "median": 12.0,
    "stable": false,
    "settings": 15,
    "spread_frac": 0.917,
    "values_grid": [
     5,
     5,
     4,
     12,
     11,
     12,
     13,
     13,
     15,
     12,
     13,
     12
    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     5,
     13,
     15
    ]
   },
   "light_off.dominant_freq_hz": {
    "max": 2.375,
    "min": 2.375,
    "median": 2.375,
    "stable": true,
    "settings": 4,
    "spread_frac": 0.0,
    "varied_over": "baseline windows",
    "values_by_baseline": {
     "678": 2.375,
     "901": 2.375,
     "1356": 2.375,
     "2712": 2.375
    }
   },
   "light_off.persistent_rotors": {
    "max": 0.0,
    "min": 0.0,
    "median": 0.0,
    "stable": true,
    "settings": 15,
    "spread_frac": 0.0,
    "values_grid": [
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0
    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     0,
     0,
     0
    ]
   },
   "light_off.singularity_frames_frac": {
    "max": 0.02955145118733509,
    "min": 0.0029023746701846965,
    "median": 0.008575197889182058,
    "stable": false,
    "settings": 12,
    "spread_frac": 3.108,
    "values_grid": [
     0.02928759894459103,
     0.02955145118733509,
     0.02691292875989446,
     0.008707124010554089,
     0.008179419525065963,
     0.00712401055408971,
     0.0036939313984168864,
     0.0036939313984168864,
     0.0029023746701846965,
     0.013192612137203167,
     0.012137203166226913,
     0.008443271767810026
    ],
    "varied_over": "filter grid"
   },
   "light_off.persistent_rotor_present": {
    "stable": true,
    "values_grid": [
     false,
     false,
     false,
     false,
     false,
     false,
     false,
     false,
     false,
     false,
     false,
     false
    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     false,
     false,
     false
    ],
    "stable_across_filters": true,
    "stable_across_trackers": true
   },
   "light_off.persistent_rotor_count_max": {
    "max": 0.0,
    "min": 0.0,
    "median": 0.0,
    "stable": true,
    "settings": 15,
    "spread_frac": 0.0,
    "values_grid": [
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0,
     0
    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     0,
     0,
     0
    ]
   },
   "illuminated_arrhythmia.dominant_freq_hz": {
    "max": 19.85,
    "min": 15.356,
    "median": 17.2285,
    "stable": false,
    "settings": 4,
    "spread_frac": 0.261,
    "varied_over": "baseline windows",
    "values_by_baseline": {
     "678": 19.85,
     "901": 19.101,
     "1356": 15.356,
     "2712": 15.356
    }
   },
   "illuminated_arrhythmia.persistent_rotors": {
    "max": 15.0,
    "min": 4.0,
    "median": 12.0,
    "stable": false,
    "settings": 15,
    "spread_frac": 0.917,
    "values_grid": [
     5,
     5,
     4,
     12,
     11,
     12,
     13,
     13,
     15,
     12,
     13,
     12
    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     5,
     13,
     15
    ]
   },
   "illuminated_after_termination.dominant_freq_hz": {
    "max": 2.214,
    "min": 2.214,
    "median": 2.214,
    "stable": true,
    "settings": 4,
    "spread_frac": 0.0,
    "varied_over": "baseline windows",
    "values_by_baseline": {
     "678": 2.214,
     "901": 2.214,
     "1356": 2.214,
     "2712": 2.214
    }
   },
   "illuminated_arrhythmia.singularity_frames_frac": {
    "max": 0.48801498127340825,
    "min": 0.3816479400749064,
    "median": 0.47191011235955055,
    "stable": true,
    "settings": 12,
    "spread_frac": 0.225,
    "values_grid": [
     0.40898876404494383,
     0.40299625468164796,
     0.3816479400749064,
     0.4797752808988764,
     0.4756554307116105,
     0.45767790262172287,
     0.48801498127340825,
     0.4846441947565543,
     0.4681647940074906,
     0.4842696629213483,
     0.47902621722846445,
     0.4606741573033708
    ],
    "varied_over": "filter grid"
   },
   "illuminated_after_termination.persistent_rotors": {
    "max": 0.0,
    "min": 0.0,
    "median": 0.0,
    "stable": true,
    "settings": 15,
    "spread_frac": 0.0,
    "values_grid": [
     0,
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     0,
     0,
     0,
     0,
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    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     0,
     0,
     0
    ]
   },
   "illuminated_arrhythmia.persistent_rotor_present": {
    "stable": true,
    "values_grid": [
     true,
     true,
     true,
     true,
     true,
     true,
     true,
     true,
     true,
     true,
     true,
     true
    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     true,
     true,
     true
    ],
    "stable_across_filters": true,
    "stable_across_trackers": true
   },
   "illuminated_arrhythmia.persistent_rotor_count_max": {
    "max": 2.0,
    "min": 1.0,
    "median": 2.0,
    "stable": false,
    "settings": 15,
    "spread_frac": 0.5,
    "values_grid": [
     1,
     1,
     1,
     2,
     2,
     2,
     2,
     2,
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     2,
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    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     1,
     2,
     2
    ]
   },
   "illuminated_after_termination.singularity_frames_frac": {
    "max": 0.014941892639734366,
    "min": 0.0005534034311012728,
    "median": 0.005534034311012729,
    "stable": false,
    "settings": 12,
    "spread_frac": 2.6,
    "values_grid": [
     0.007194244604316547,
     0.007194244604316547,
     0.007194244604316547,
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     0.003320420586607637,
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    "varied_over": "filter grid"
   },
   "illuminated_after_termination.persistent_rotor_present": {
    "stable": true,
    "values_grid": [
     false,
     false,
     false,
     false,
     false,
     false,
     false,
     false,
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    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     false,
     false,
     false
    ],
    "stable_across_filters": true,
    "stable_across_trackers": true
   },
   "illuminated_after_termination.persistent_rotor_count_max": {
    "max": 0.0,
    "min": 0.0,
    "median": 0.0,
    "stable": true,
    "settings": 15,
    "spread_frac": 0.0,
    "values_grid": [
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    ],
    "varied_over": "filter grid + trackers",
    "values_trackers": [
     0,
     0,
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   }
  },
  "reviewed_at": "2026-10-27T23:36:57.792845+00:00",
  "recording_id": "55cb4aa3-6502-45a6-a14c-85cb676fe8c3",
  "signature_id": "b456870e-cc99-40a9-aff1-55e4133116c4",
  "prompt_version": "critic-v1",
  "criteria_status": {
   "note": null,
   "rules": [
    {
     "id": "physiology_reference_rates",
     "expert": "cardiac electrophysiologist per species",
     "status": "provisional",
     "values": {
      "ranges": [
       "mouse_spiral_rotation_hz"
      ],
      "tolerance_frac": 0.25,
      "segment_rhythm_rule": "expected persistent rotors 'present' -> spiral arrhythmia"
     },
     "decision": null,
     "location": "worker/voltage/physiology.py (RANGES, TOLERANCE_FRAC)",
     "reviewed": false,
     "reviewer": null,
     "description": "Cited physiological ranges (single-study values widened by a 25% tolerance), applied to segments by their expected rhythm; used by the critic and for frame-rate sanity checks",
     "reviewed_at": null
    },
    {
     "id": "stability_rule",
     "expert": "biostatistician + optical mapping analyst",
     "status": "provisional",
     "values": {
      "unstable": [
       "light_off.singularity_frames_frac",
       "illuminated_arrhythmia.persistent_rotors",
       "illuminated_arrhythmia.persistent_rotor_count_max",
       "illuminated_arrhythmia.dominant_freq_hz",
       "illuminated_after_termination.singularity_frames_frac",
       "persistent_rotor_tracks"
      ],
      "stable_frac": 0.25
     },
     "decision": null,
     "location": "worker/agents/critic.py (STABLE_FRAC, stability)",
     "reviewed": false,
     "reviewer": null,
     "description": "A metric is reportable only if its spread across all sensitivity settings is <= 25% of its median (zero spread when all values are 0); otherwise 'unstable, not reportable'",
     "reviewed_at": null
    },
    {
     "id": "persistence_threshold_variants",
     "expert": "computational cardiac electrophysiologist (phase mapping)",
     "status": "provisional",
     "values": {
      "measured_cycle": 52,
      "paper_rotation": 50
     },
     "decision": null,
     "location": "worker/agents/critic.py (persistence_variants)",
     "reviewed": false,
     "reviewer": null,
     "description": "The persistent-rotor rule is run at two lifetimes, one measured cycle of the fastest segment and the paper's cited rotation period; both verdicts stored, disagreement flagged",
     "reviewed_at": null
    },
    {
     "id": "persistent_rotor_criterion",
     "expert": "cardiac electrophysiologist",
     "status": "provisional",
     "values": {
      "max_absent": 0,
      "min_present": 1
     },
     "decision": null,
     "location": "worker/voltage/sensitivity.py (MIN_ROTORS_PRESENT, MAX_ROTORS_ABSENT)",
     "reviewed": false,
     "reviewer": null,
     "description": "Persistent-rotor finding holds if every 'present' segment has >= 1 persistent rotor and every 'absent' segment has none, at every setting",
     "reviewed_at": null
    },
    {
     "id": "sensitivity_grid",
     "expert": "optical mapping analyst",
     "status": "provisional",
     "values": {
      "spatial_sigma": {
       "light": 0.5,
       "default": 1.0,
       "heavier": 2.0
      },
      "baseline_frames": {
       "run": 901,
       "3x_cycle": 1356,
       "6x_cycle": 2712,
       "1.5x_cycle": 678
      },
      "baseline_scaling": {
       "multiples": {
        "3x_cycle": 3.0,
        "6x_cycle": 6.0,
        "1.5x_cycle": 1.5
       },
       "reference_segment": "illuminated_after_termination",
       "segment_cycles_frames": {
        "light_off": 421,
        "illuminated_arrhythmia": 52,
        "illuminated_after_termination": 452
       },
       "reference_cycle_frames": 452,
       "window_over_cycle_per_segment": {
        "run": {
         "light_off": 2.14,
         "illuminated_arrhythmia": 17.33,
         "illuminated_after_termination": 1.99
        },
        "3x_cycle": {
         "light_off": 3.22,
         "illuminated_arrhythmia": 26.08,
         "illuminated_after_termination": 3.0
        },
        "6x_cycle": {
         "light_off": 6.44,
         "illuminated_arrhythmia": 52.15,
         "illuminated_after_termination": 6.0
        },
        "1.5x_cycle": {
         "light_off": 1.61,
         "illuminated_arrhythmia": 13.04,
         "illuminated_after_termination": 1.5
        }
       }
      },
      "tracker(link_px, max_gap)": {
       "loose": [
        6.0,
        10
       ],
       "strict": [
        2.0,
        1
       ],
       "default": [
        4.0,
        5
       ]
      }
     },
     "decision": null,
     "location": "worker/voltage/sensitivity.py (SIGMAS, BASELINE_MULTIPLES, baseline_levels)",
     "reviewed": false,
     "reviewer": null,
     "description": "Filter levels tested: spatial sigma and baseline window values",
     "reviewed_at": null
    }
   ],
   "status": "provisional",
   "all_reviewed": false,
   "superseded_by_run": null
  },
  "persistence_variants": {
   "agree": true,
   "measured_cycle": {
    "basis": "one dominant cycle of the fastest segment at the run setting",
    "applicable": true,
    "min_frames": 52,
    "segment_counts_grid": {
     "light_off": [
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      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0
     ],
     "illuminated_arrhythmia": [
      5,
      5,
      4,
      12,
      11,
      12,
      13,
      13,
      15,
      12,
      13,
      12
     ],
     "illuminated_after_termination": [
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0
     ]
    },
    "holds_across_filters": true,
    "label_across_filters": "holds (provisional)",
    "holds_across_trackers": true,
    "label_across_trackers": "holds (provisional)",
    "segment_lifetimes_run": {
     "light_off": [],
     "illuminated_arrhythmia": [
      40,
      34,
      57,
      106,
      37,
      57,
      41,
      34,
      62,
      21,
      37,
      32,
      23
     ],
     "illuminated_after_termination": []
    }
   },
   "paper_rotation": {
    "ref": "10.1371/journal.pcbi.1011660",
    "basis": "1000 frames/s / 20 Hz, cited",
    "passage": " is shown in Fig 3B. It shows that the arrhythmia consists of a single spiral wave with a stationary core dynamic and a rotational frequency of \u2248 20 Hz before illumination. During a single global optical pulse with a PL of 5000 ms and an LI of 3.21 \u03bcW/mm2, the frequency of the arrhythmia de",
    "applicable": true,
    "min_frames": 50,
    "rotation_hz": 20.0,
    "segment_counts_grid": {
     "light_off": [
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0
     ],
     "illuminated_arrhythmia": [
      5,
      5,
      4,
      12,
      11,
      12,
      13,
      13,
      15,
      12,
      13,
      12
     ],
     "illuminated_after_termination": [
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0,
      0
     ]
    },
    "holds_across_filters": true,
    "label_across_filters": "holds (provisional)",
    "holds_across_trackers": true,
    "label_across_trackers": "holds (provisional)",
    "segment_lifetimes_run": {
     "light_off": [],
     "illuminated_arrhythmia": [
      40,
      34,
      57,
      106,
      37,
      57,
      41,
      34,
      62,
      21,
      37,
      32,
      23
     ],
     "illuminated_after_termination": []
    }
   }
  },
  "required_review_topics": [
   "unstable:light_off.singularity_frames_frac",
   "unstable:illuminated_arrhythmia.persistent_rotors",
   "unstable:illuminated_arrhythmia.persistent_rotor_count_max",
   "unstable:illuminated_arrhythmia.dominant_freq_hz",
   "unstable:illuminated_after_termination.singularity_frames_frac",
   "unstable:persistent_rotor_tracks"
  ]
 },
 "criteria": [
  {
   "criterion": "Singularities present where the design expects them, absent elsewhere",
   "rule": "each 'present' segment: frac >= 0.1 and >= 2.0 x max frac over 'absent' segments, at every setting",
   "result": "holds at 12 filter settings",
   "superseded": false,
   "provisional": true
  },
  {
   "criterion": "Persistent rotors present where the design expects them, absent elsewhere",
   "rule": "each 'present' segment: count >= 1; each 'absent' segment: count <= 0, at every setting",
   "result": "holds at 12 filter settings and 3 trackers",
   "superseded": false,
   "provisional": true
  },
  {
   "criterion": "Persistence threshold, paper context",
   "rule": "lifetime \u2265 52 frames (measured cycle) and \u2265 50 frames (cited 20 Hz)",
   "result": "agree",
   "provisional": true
  }
 ],
 "report": {
  "methods": "Recording Mouse heart, spiral wave and optogenetic termination (M13Rec001) (doi:10.5281/zenodo.10228296; 64x55 px, 9267 frames, 1000 Hz) was analysed over frames 500-8767. Deposit shows signs of prior processing (provisional): negative values, non integer, nan mask all frames, temporal smoothing, spatial smoothing. Each pixel was baseline-corrected by subtracting a 901-frame centered moving average; NaN pixels were set to zero. Dye polarity (inverted) was taken from the sign of the median per-pixel skew of dV/dt. For phase only, each frame was spatially filtered with a Gaussian (sigma 1.0 px, truncated at 4.0 sigma); no temporal low-pass was applied. Phase was the angle of the Hilbert transform with 500 frames of padding on each side. Phase singularities were plaquettes with |winding| > 0.9 turns at least 3 px inside the tissue edge; they were tracked across frames (same charge, <= 4.0 px per frame, gaps <= 5 frames), and a persistent rotor was a track lasting >= 52 frames (1 cycle(s) of the fastest segment) within 3.0 px of an opposite-charge singularity in no more than 50% of its frames. Acquisition log (LED trigger channel, provisional interpretation): illumination on over frames 500-4977 of the analysed frames 500-8767. Segments (provisional, project lead (not a domain scientist), following the paper's design): illumination with arrhythmia frames 500-3170 (expected persistent rotors: present); illumination after termination frames 3170-4977 (expected persistent rotors: absent); light off frames 4977-8767 (expected persistent rotors: absent). Sensitivity: baseline 2712, 1356, 678, 901 frames x sigma 0.5, 1.0, 2.0 px, and tracker variants. singularities: across filters holds (provisional). persistent rotors: across filters holds (provisional); across trackers holds (provisional). persistent rotors fraction superseded: across filters does not hold (provisional); across trackers does not hold (provisional). All thresholds and criteria are provisional pending review by a domain scientist.",
  "rules": [
   {
    "id": "protocol_parameter_set",
    "description": "Each protocol's fixed, versioned analysis parameters (version 1 = developer defaults); no run or agent may deviate",
    "expert": "optical mapping analyst",
    "status": "provisional",
    "location": "worker/voltage/protocol_params.py (developer_defaults, set_params)",
    "values": {
     "set_by": "developer (not a domain scientist)",
     "protocol": "Mouse whole heart optical mapping (Luther lab)",
     "protocol_id": "f65d786f-f194-4be2-88b8-10d3dd25d674",
     "params_version": 3
    }
   },
   {
    "id": "baseline_window_rule",
    "description": "A run proceeds only if the protocol's baseline window is >= 2x the slowest segment's cycle, the cycle from the MAP channel when a DAQ log exists, else from per-pixel dominant frequency on linearly detrended pixels; otherwise the run is held by code",
    "expert": "optical mapping analyst",
    "status": "provisional",
    "location": "worker/voltage/baseline_rule.py (FACTOR, evaluate)",
    "values": {
     "ok": true,
     "factor": 2.0,
     "source": "MAP channel (DAQ log)",
     "required_min_frames": 830,
     "slowest_cycle_frames": 415
    }
   },
   {
    "id": "filter_defaults",
    "description": "Default baseline window (frames) and spatial Gaussian sigma/truncate for phase",
    "expert": "optical mapping analyst (cardiac electrophysiology)",
    "status": "provisional",
    "location": "worker/voltage/preprocess.py (Params)",
    "values": {
     "lowpass": null,
     "spatial_sigma": 1.0,
     "baseline_frames": 901,
     "spatial_truncate": 4.0
    }
   },
   {
    "id": "tissue_mask",
    "description": "Tissue = not NaN in frame 0 and nonzero temporal std",
    "expert": "optical mapping analyst",
    "status": "provisional",
    "location": "worker/voltage/io.py (tissue_mask)",
    "values": {
     "rule": "not NaN in frame 0 and nonzero std",
     "tissue_pixels": 2332
    }
   },
   {
    "id": "polarity",
    "description": "Dye polarity from sign of median per-pixel skew of dV/dt",
    "expert": "optical mapping analyst / voltage dye chemist",
    "status": "provisional",
    "location": "worker/voltage/preprocess.py (polarity)",
    "values": {
     "method": "median skew of dV/dt",
     "result": -1
    }
   },
   {
    "id": "singularity_detection",
    "description": "Phase singularity = |winding| > threshold turns, >= erode px from tissue edge",
    "expert": "computational cardiac electrophysiologist (phase mapping)",
    "status": "provisional",
    "location": "worker/voltage/preprocess.py (Params.rotor_threshold, rotor_erode_px)",
    "values": {
     "rotor_erode_px": 3,
     "rotor_threshold": 0.9
    }
   },
   {
    "id": "rotor_persistence",
    "description": "Track linking distance/gap and minimum lifetime for a persistent rotor",
    "expert": "computational cardiac electrophysiologist (phase mapping)",
    "status": "provisional",
    "location": "worker/voltage/rotors.py (TrackParams)",
    "values": {
     "link_px": 4.0,
     "max_gap": 5,
     "min_cycles": 1.0,
     "min_frames": 52
    }
   },
   {
    "id": "chirality_pairing",
    "description": "Opposite-charge singularities within pair distance are a pair; tracks paired most of their life are excluded from rotors",
    "expert": "computational cardiac electrophysiologist (phase mapping)",
    "status": "provisional",
    "location": "worker/voltage/rotors.py (TrackParams.pair_dist_px, paired_frac)",
    "values": {
     "paired_frac": 0.5,
     "pair_dist_px": 3.0
    }
   },
   {
    "id": "sensitivity_grid",
    "description": "Filter levels tested: spatial sigma and baseline window values",
    "expert": "optical mapping analyst",
    "status": "provisional",
    "location": "worker/voltage/sensitivity.py (SIGMAS, BASELINE_MULTIPLES, baseline_levels)",
    "values": {
     "sigmas": {
      "light": 0.5,
      "default": 1.0,
      "heavier": 2.0
     },
     "trackers": {
      "loose": [
       6.0,
       10
      ],
      "strict": [
       2.0,
       1
      ],
      "default": [
       4.0,
       5
      ]
     },
     "baselines": {
      "run": 901,
      "3x_cycle": 1356,
      "6x_cycle": 2712,
      "1.5x_cycle": 678
     }
    }
   },
   {
    "id": "analysis_window",
    "description": "Frames analysed: whole recording minus one filter pad at each end (unless the plan narrows it)",
    "expert": "cardiac electrophysiologist familiar with the dataset",
    "status": "provisional",
    "location": "worker/voltage/runs.py (default_window)",
    "values": {
     "f0": 500,
     "f1": 8767
    }
   },
   {
    "id": "prior_processing_flags",
    "description": "Thresholds for flagging depositor processing (normalization, masking, temporal/spatial smoothing)",
    "expert": "imaging scientist (camera acquisition and noise)",
    "status": "provisional",
    "location": "worker/voltage/inspect.py (prior_processing)",
    "values": {
     "flags": [
      "negative_values",
      "non_integer",
      "nan_mask_all_frames",
      "temporal_smoothing",
      "spatial_smoothing"
     ],
     "thresholds": {
      "int_frac": 0.5,
      "neg_frac": 0.01,
      "dv_autocorr": 0.5,
      "neighbour_corr": 0.8
     }
    }
   },
   {
    "id": "baseline_step_detection",
    "description": "Baseline step = consensus upward step in tissue-mean raw baseline (cause not inferred; first misread as light onset, contradicted by the DAQ)",
    "expert": "optical mapping experimentalist",
    "status": "provisional",
    "location": "worker/voltage/events.py (detect_baseline_step)",
    "values": {
     "frames": [
      3170
     ]
    }
   },
   {
    "id": "daq_interpretation",
    "description": "DAQ channel names from depositor notebook; frames = first N triggers of closest burst; midpoint thresholds",
    "expert": "experimentalist who recorded the data (or the depositor)",
    "status": "provisional",
    "location": "worker/voltage/daq.py",
    "values": {
     "events": [
      "illumination_on@0",
      "arrhythmia_termination@3153",
      "illumination_off@4977"
     ]
    }
   },
   {
    "id": "segment_definitions",
    "description": "Mouse segments bounded by DAQ light events and the baseline step, interpreted as spiral termination under illumination (project lead, from Hussaini et al. 2023)",
    "expert": "cardiac electrophysiologist (ideally the depositing authors)",
    "status": "provisional",
    "location": "worker/voltage/annotations.py (MOUSE_SEGMENTS)",
    "values": {
     "light_off": [
      4977,
      9267
     ],
     "illuminated_arrhythmia": [
      0,
      3170
     ],
     "illuminated_after_termination": [
      3170,
      4977
     ]
    }
   },
   {
    "id": "rotor_finding_criterion",
    "description": "Singularity before/after finding holds if frac(before) >= min_frac and >= min_ratio x frac(after) at every setting (also kept, superseded, for persistent rotors)",
    "expert": "cardiac electrophysiologist + biostatistician",
    "status": "provisional",
    "location": "worker/voltage/sensitivity.py (MIN_FRAC, MIN_RATIO)",
    "values": {
     "min_frac": 0.1,
     "min_ratio": 2.0
    }
   },
   {
    "id": "persistent_rotor_criterion",
    "description": "Persistent-rotor finding holds if every 'present' segment has >= 1 persistent rotor and every 'absent' segment has none, at every setting",
    "expert": "cardiac electrophysiologist",
    "status": "provisional",
    "location": "worker/voltage/sensitivity.py (MIN_ROTORS_PRESENT, MAX_ROTORS_ABSENT)",
    "values": {
     "expect": {
      "light_off": "absent",
      "illuminated_arrhythmia": "present",
      "illuminated_after_termination": "absent"
     },
     "max_absent": 0,
     "min_present": 1,
     "spanning_rotor": "counts in every segment it overlaps",
     "min_lifetime_frames": 52
    }
   },
   {
    "id": "physiology_reference_rates",
    "description": "Cited physiological ranges (single-study values widened by a 25% tolerance), applied to segments by their expected rhythm; used by the critic and for frame-rate sanity checks",
    "expert": "cardiac electrophysiologist per species",
    "status": "provisional",
    "location": "worker/voltage/physiology.py (RANGES, TOLERANCE_FRAC)",
    "values": {
     "ranges": [
      "mouse_spiral_rotation_hz"
     ],
     "tolerance_frac": 0.25,
     "segment_rhythm_rule": "expected persistent rotors 'present' -> spiral arrhythmia"
    }
   },
   {
    "id": "stability_rule",
    "description": "A metric is reportable only if its spread across all sensitivity settings is <= 25% of its median (zero spread when all values are 0); otherwise 'unstable, not reportable'",
    "expert": "biostatistician + optical mapping analyst",
    "status": "provisional",
    "location": "worker/agents/critic.py (STABLE_FRAC, stability)",
    "values": {
     "unstable": [
      "light_off.singularity_frames_frac",
      "illuminated_arrhythmia.persistent_rotors",
      "illuminated_arrhythmia.persistent_rotor_count_max",
      "illuminated_arrhythmia.dominant_freq_hz",
      "illuminated_after_termination.singularity_frames_frac",
      "persistent_rotor_tracks"
     ],
     "stable_frac": 0.25
    }
   },
   {
    "id": "persistence_threshold_variants",
    "description": "The persistent-rotor rule is run at two lifetimes, one measured cycle of the fastest segment and the paper's cited rotation period; both verdicts stored, disagreement flagged",
    "expert": "computational cardiac electrophysiologist (phase mapping)",
    "status": "provisional",
    "location": "worker/agents/critic.py (persistence_variants)",
    "values": {
     "measured_cycle": 52,
     "paper_rotation": 50
    }
   }
  ],
  "review_items": [
   {
    "topic": "unstable:light_off.singularity_frames_frac",
    "detail": "Review the filter sensitivity before reporting the light_off singularity-frame fraction; use only the range 0.0029023746701846965\u20130.02955145118733509 for review, not a single value.",
    "severity": "warn",
    "reviewer": "domain scientist / signal-processing reviewer"
   },
   {
    "topic": "unstable:illuminated_arrhythmia.persistent_rotors",
    "detail": "Review rotor tracking/count sensitivity; the illuminated_arrhythmia persistent-rotor count spans 4.0\u201315.0 and is not reportable as a single count.",
    "severity": "warn",
    "reviewer": "domain scientist / tracking reviewer"
   },
   {
    "topic": "unstable:illuminated_arrhythmia.persistent_rotor_count_max",
    "detail": "Review concurrent rotor-count sensitivity; the maximum concurrent count spans 1.0\u20132.0 and should not be reported as a single value.",
    "severity": "warn",
    "reviewer": "domain scientist / tracking reviewer"
   },
   {
    "topic": "unstable:illuminated_arrhythmia.dominant_freq_hz",
    "detail": "Review baseline-window dependence of the illuminated_arrhythmia frequency; it spans 15.356\u201319.85 Hz and is not reportable as a single value despite cited same-study context (DOI 10.1371/journal.pcbi.1011660).",
    "severity": "warn",
    "reviewer": "domain scientist / rhythm reviewer"
   },
   {
    "topic": "unstable:illuminated_after_termination.singularity_frames_frac",
    "detail": "Review filter sensitivity before reporting the after-termination singularity-frame fraction; use only the range 0.0005534034311012728\u20130.014941892639734366 for review.",
    "severity": "warn",
    "reviewer": "domain scientist / signal-processing reviewer"
   },
   {
    "topic": "unstable:persistent_rotor_tracks",
    "detail": "Review persistent-track counting sensitivity; total persistent tracks span 4.0\u201315.0 and are not reportable as a single value.",
    "severity": "warn",
    "reviewer": "domain scientist / tracking reviewer"
   },
   {
    "topic": "Pre-deposit processing / raw-data label",
    "detail": "The README labels M13Rec001 as raw experimental data, but notebook and measurement flags indicate masking, spatial smoothing, temporal smoothing, and normalization; avoid analyses that require raw photon counts or independent pixel noise if treated as raw camera data.",
    "severity": "warn",
    "reviewer": "data curator / domain scientist"
   },
   {
    "topic": "Event interpretation at frame 3170",
    "detail": "Frame 3170 is a baseline_step only; illumination began before frame 0 and ended at frame 4977, so frame 3170 should not be treated as light onset. The stored spiral-termination label is provisional.",
    "severity": "warn",
    "reviewer": "domain scientist"
   },
   {
    "topic": "Baseline and illumination artifact",
    "detail": "Blue stimulation light crosstalk, re-normalization by stimulation light signal, a large slow baseline range, and a baseline step can affect absolute baseline or amplitude analyses.",
    "severity": "warn",
    "reviewer": "domain scientist / signal-processing reviewer"
   },
   {
    "topic": "Provisional tool thresholds",
    "detail": "Event detection, processing flags, SNR, rhythm, reference-rate thresholds, the stability threshold, and criteria are provisional and should be checked for critical analyses.",
    "severity": "info",
    "reviewer": "domain scientist"
   }
  ],
  "reportable": [
   {
    "metric": "persistent rotor tracks",
    "segment": "all",
    "value": "4\u201315",
    "unit": "count",
    "status": "unstable, not reportable"
   },
   {
    "metric": "dominant freq (Hz)",
    "segment": "light off",
    "value": "2.375",
    "unit": "Hz",
    "status": "no cited range"
   },
   {
    "metric": "persistent rotors",
    "segment": "light off",
    "value": "0",
    "unit": "count",
    "status": "no cited range"
   },
   {
    "metric": "singularity frames fraction",
    "segment": "light off",
    "value": "0.0029\u20130.0296",
    "unit": "fraction of frames",
    "status": "unstable, not reportable"
   },
   {
    "metric": "persistent rotor count max",
    "segment": "light off",
    "value": "0",
    "unit": "count",
    "status": "no cited range"
   },
   {
    "metric": "dominant freq (Hz)",
    "segment": "illuminated arrhythmia",
    "value": "15.4\u201319.9",
    "unit": "Hz",
    "status": "unstable, not reportable"
   },
   {
    "metric": "persistent rotors",
    "segment": "illuminated arrhythmia",
    "value": "4\u201315",
    "unit": "count",
    "status": "unstable, not reportable"
   },
   {
    "metric": "dominant freq (Hz)",
    "segment": "illuminated after termination",
    "value": "2.214",
    "unit": "Hz",
    "status": "no cited range"
   },
   {
    "metric": "singularity frames fraction",
    "segment": "illuminated arrhythmia",
    "value": "0.479",
    "unit": "fraction of frames",
    "status": "no cited range"
   },
   {
    "metric": "persistent rotors",
    "segment": "illuminated after termination",
    "value": "0",
    "unit": "count",
    "status": "no cited range"
   },
   {
    "metric": "persistent rotor count max",
    "segment": "illuminated arrhythmia",
    "value": "1\u20132",
    "unit": "count",
    "status": "unstable, not reportable"
   },
   {
    "metric": "singularity frames fraction",
    "segment": "illuminated after termination",
    "value": "0.000553\u20130.0149",
    "unit": "fraction of frames",
    "status": "unstable, not reportable"
   },
   {
    "metric": "persistent rotor count max",
    "segment": "illuminated after termination",
    "value": "0",
    "unit": "count",
    "status": "no cited range"
   }
  ],
  "verdict": {
   "physiology_ok": null,
   "send_back": false,
   "notes": "Verdict: report only the stable, provisional signature components; physiology_ok is null because the only cited-range check, illuminated_arrhythmia.dominant_freq_hz, is unstable across baseline windows (15.356\u201319.85 Hz) and therefore not reportable as a single value, even though the same-study context gives approximately 18.75\u201320.0 Hz and a checked range of 14.0625\u201325.0 Hz (DOI 10.1371/journal.pcbi.1011660). Reportable with caveats: stable absence of persistent rotors in light_off and illuminated_after_termination (0 across filter and tracker variants), stable light_off and illuminated_after_termination dominant frequencies of 2.375 Hz and 2.214 Hz without cited ranges, and stable illuminated_arrhythmia singularity-frame fraction as a range of 0.3816479400749064\u20130.48801498127340825 without a cited range; unstable and not reportable as single values are light_off.singularity_frames_frac (0.0029023746701846965\u20130.02955145118733509), illuminated_arrhythmia.persistent_rotors and persistent_rotor_tracks (4.0\u201315.0), illuminated_arrhythmia.persistent_rotor_count_max (1.0\u20132.0), illuminated_arrhythmia.dominant_freq_hz (15.356\u201319.85 Hz), and illuminated_after_termination.singularity_frames_frac (0.0005534034311012728\u20130.014941892639734366). The persistent-rotor rule itself holds under both min_frames 52 and min_frames 50, and strict/default/loose tracker rule verdicts agree even though counts differ; review the processed-data status, frame 3170 event interpretation, baseline/illumination artifact, and provisional thresholds. The ranges, the stability threshold and the criteria are provisional."
  },
  "provenance": {
   "recording": {
    "id": "55cb4aa3-6502-45a6-a14c-85cb676fe8c3",
    "label": "Mouse heart, spiral wave and optogenetic termination (M13Rec001)",
    "source": "public",
    "source_ref": "10.5281/zenodo.10228296",
    "publication_ref": "10.1371/journal.pcbi.1011660",
    "storage_path": "public/M13Rec001_complete.npy",
    "format": "npy",
    "sha256": "3f8f2e1b8f776633089b33ccd4bf3fccb4f13140b71991f1dcd0e0a12bb48cbc",
    "size_bytes": 260958848,
    "license": "CC-BY-4.0",
    "attribution": "Hussaini, Sayedeh; Luther, Stefan; L\u00e4dke, Sarah L.",
    "rights_source": {
     "ref": "10.5281/zenodo.10228296",
     "url": "https://zenodo.org/records/10228296",
     "kind": "deposit_metadata",
     "creators": [
      "Hussaini, Sayedeh",
      "Luther, Stefan",
      "L\u00e4dke, Sarah L."
     ],
     "license_as_stated": "cc-by-4.0"
    },
    "frame_rate_hz": 1000,
    "frame_rate_source": {
     "ref": "10.1371/journal.pcbi.1011660",
     "kind": "publication",
     "note": "Camera frames are 64 x 64 in the paper; the deposit is 64 x 55 (cropped). Consistent with the DAQ: 10 samples per frame and a 5 s light pulse spanning 50,001 samples imply a 10 kHz DAQ.",
     "quote": " 775 \u00b1 70nm bandpass filter (FF01\u2013775/140-25, Semrock) and finally by the camera (EMCCD, Cascade 128+, Photometrics) with a spatial resolution of 64 \u00d7 64 pixels (133 \u03bcm per pixel) at 1 kHz. Optical Mapping recordings were acquired with software MultiRecorder and analysed with software PythonAnalyser (both developed by Research Group Biomedical Physics). Electrical s",
     "section": "Materials and methods: Optical mapping experiments on ventricular arrhythmia and its termination in the intact mouse heart"
    },
    "pixel_size_um": 133,
    "pixel_size_source": {
     "ref": "10.1371/journal.pcbi.1011660",
     "kind": "publication",
     "note": "paper states 64 x 64 px at 133 um; the deposit is 64 x 55 (cropped, not rebinned)",
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}